Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.E20V

c.59A>T

Surrounding Variants

1 paper

NM_017449.5

p.V19V

c.57G>C

1 paper

NM_017449.5

p.V19E

c.56T>A

1 paper

NM_017449.5

p.E21D

c.63A>C

1 paper

NM_017449.5

p.E21D

c.63A>T

2 papers

NM_017449.5

p.A18D

c.53C>A

1 paper

NM_017449.5

p.A18G

c.53C>G

1 paper

NM_017449.5

p.A18V

c.53C>T

1 paper

NM_017449.5

p.A18T

c.52G>A

1 paper

NM_017449.5

p.A17A

c.51C>A

2 papers

NM_017449.5

p.L16I

c.46C>A

1 paper

NM_017449.5

p.P14S

c.40C>T

2 papers

NM_017449.5

p.L13P

c.38T>C