Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.L33P

c.98T>C

Surrounding Variants

5 papers

NM_017449.5

p.L33R

c.98T>G

1 paper

NM_017449.5

p.L33_G34ins6

c.97_101ins18

3 papers

NM_017449.5

p.G34R

c.100G>C

1 paper

NM_017449.5

p.G34A

c.101G>C

1 paper

NM_017449.5

p.G34G

c.102C>T

1 paper

NM_017449.5

p.A31A

c.93T>A

1 paper

NM_017449.5

p.W35R

c.103T>A

1 paper

NM_017449.5

p.W35*

c.104G>A

1 paper

NM_017449.5

p.A31T

c.91G>A

1 paper

NM_017449.5

p.A31S

c.91G>T

1 paper

NM_017449.5

p.M36V

c.106A>G

1 paper

NM_017449.5

p.M36L

c.106A>T