Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.P40P

c.120A>T

Surrounding Variants

1 paper

NM_017449.5

p.P40R

c.119C>G

1 paper

NM_017449.5

p.P40T

c.118C>A

1 paper

NM_017449.5

p.P40S

c.118C>T

1 paper

NM_017449.5

p.P39H

c.116C>A

2 papers

NM_017449.5

p.P39A

c.115C>G

1 paper

NM_017449.5

p.G42Fs

c.125delinsTTFs

1 paper

NM_017449.5

p.V37A

c.110T>C

1 paper

NM_017449.5

p.V37M

c.109G>A

1 paper

NM_017449.5

p.M36I

c.108G>A

1 paper

NM_017449.5

p.M36V

c.106A>G

1 paper

NM_017449.5

p.M36L

c.106A>T

1 paper

NM_017449.5

p.W35*

c.104G>A