Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.N52I

c.155A>T

Surrounding Variants

1 paper

NM_017449.5

p.E51V

c.152A>T

1 paper

NM_017449.5

p.M53K

c.158T>A

2 papers

NM_017449.5

p.M53_T58del0

c.159_173del15

1 paper

NM_017449.5

p.M53I

c.159G>A

1 paper

NM_017449.5

p.M53I

c.159G>C

1 paper

NM_017449.5

p.M53I

c.159G>T

3 papers

NM_017449.5

p.N54Y

c.160A>T

1 paper

NM_017449.5

p.E51delFs

c.151_152delGA

11 papers

NM_017449.5

p.Y49F

c.146A>T

2 papers

NM_017449.5

p.T55K

c.164C>A

1 paper

NM_017449.5

p.T55insFs

c.164_165insG

2 papers

NM_017449.5

p.T55M

c.164C>T