Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.E66Q

c.196G>C

Surrounding Variants

1 paper

NM_017449.5

p.E66_L73del0

c.198_218del21

1 paper

NM_017449.5

p.S67ins1

c.200_201insTCC

1 paper

NM_017449.5

p.V64A

c.191T>C

1 paper

NM_017449.5

p.S68R

c.202A>C

1 paper

NM_017449.5

p.N63K

c.189C>A

1 paper

NM_017449.5

p.S68I

c.203G>T

2 papers

NM_017449.5

p.N63S

c.188A>G

1 paper

NM_017449.5

p.N63Y

c.187A>T

1 paper

NM_017449.5

p.Q69L

c.206A>T

1 paper

NM_017449.5

p.Q69H

c.207G>C

1 paper

NM_017449.5

p.C62insFs

c.185_186insA

1 paper

NM_017449.5

p.C62G

c.184T>G