Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.H84L

c.251A>T

Surrounding Variants

1 paper

NM_017449.5

p.H84P

c.251A>C

1 paper

NM_017449.5

p.H84Q

c.252C>G

2 papers

NM_017449.5

p.H84Y

c.250C>T

1 paper

NM_017449.5

p.R85G

c.253C>G

4 papers

NM_017449.5

p.R85C

c.253C>T

1 paper

NM_017449.5

p.A83V

c.248C>T

6 papers

NM_017449.5

p.R85H

c.254G>A

1 paper

NM_017449.5

p.R85L

c.254G>T

2 papers

NM_017449.5

p.A83T

c.247G>A

1 paper

NM_017449.5

p.G82A

c.245G>C

1 paper

NM_017449.5

p.G82R

c.244G>C

1 paper

NM_017449.5

p.R81H

c.242G>A