Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.D96D

c.288C>T

Surrounding Variants

1 paper

NM_017449.5

p.D96G

c.287A>G

1 paper

NM_017449.5

p.D96N

c.286G>A

1 paper

NM_017449.5

p.R95C

c.283C>T

1 paper

NM_017449.5

p.S98_P104del0

c.294_311del18

1 paper

NM_017449.5

p.V94A

c.281T>C

2 papers

NM_017449.5

p.S93L

c.278C>T

1 paper

NM_017449.5

p.S93T

c.277T>A

1 paper

NM_017449.5

p.S93A

c.277T>G

1 paper

NM_017449.5

p.S102_K108insFs

c.304_323dup20

1 paper

NM_017449.5

p.M90I

c.270G>A

1 paper

NM_017449.5

p.M90I

c.270G>C

1 paper

NM_017449.5

p.M90I

c.270G>T