Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.G105G

c.315C>T

Surrounding Variants

1 paper

NM_017449.5

p.S106T

c.316T>A

1 paper

NM_017449.5

p.S106F

c.317C>T

1 paper

NM_017449.5

p.G105_S106delFs

c.314_317del4

1 paper

NM_017449.5

p.C107C

c.321C>T

1 paper

NM_017449.5

p.V103V

c.309G>A

4 papers

NM_017449.5

p.V103M

c.307G>A

1 paper

NM_017449.5

p.K108K

c.324G>A

1 paper

NM_017449.5

p.K108N

c.324G>C

1 paper

NM_017449.5

p.K108N

c.324G>T

1 paper

NM_017449.5

p.E109G

c.326A>G

1 paper

NM_017449.5

p.S102_K108insFs

c.304_323dup20

1 paper

NM_017449.5

p.E109E

c.327G>A