Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.S170S

c.510C>T

Surrounding Variants

1 paper

NM_017449.5

p.R171C

c.511C>T

2 papers

NM_017449.5

p.S172_S186del15

c.514_557del45

1 paper

NM_017449.5

p.S170_C184del15

c.508_551del45

1 paper

NM_017449.5

p.V169E

c.506T>A

1 paper

NM_017449.5

p.V169A

c.506T>C

1 paper

NM_017449.5

p.V169L

c.505G>C

1 paper

NM_017449.5

p.V169L

c.505G>T

1 paper

NM_017449.5

p.S172I

c.515G>T

2 papers

NM_017449.5

p.G173D

c.518G>A

1 paper

NM_017449.5

p.G167E

c.500G>A

1 paper

NM_017449.5

p.G167A

c.500G>C

1 paper

NM_017449.5

p.G167*

c.499G>T