Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_017449.5

p.A189V

c.566C>T

Surrounding Variants

1 paper

NM_017449.5

p.A189S

c.565G>T

1 paper

NM_017449.5

p.V190M

c.568G>A

1 paper

NM_017449.5

p.I188delFs

c.563delT

2 papers

NM_017449.5

p.R191H

c.572G>A

1 paper

NM_017449.5

p.L187P

c.560T>C

1 paper

NM_017449.5

p.S186S

c.558C>A

1 paper

NM_017449.5

p.V192I

c.574G>A

1 paper

NM_017449.5

p.F193delFs

c.578delT

1 paper

NM_017449.5

p.S186A

c.556T>G

1 paper

NM_017449.5

p.F193I

c.577T>A

1 paper

NM_017449.5

p.F193L

c.577T>C

1 paper

NM_017449.5

p.F193Y

c.578T>A