Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_017449.5

p.A279S

c.835G>T

Surrounding Variants

1 paper

NM_017449.5

p.A279V

c.836C>T

1 paper

NM_017449.5

p.A279delFs

c.835delG

1 paper

NM_017449.5

p.K278*

c.832A>T

1 paper

NM_017449.5

p.K278fs

c.832_833fs

1 paper

NM_017449.5

p.G282W

c.844G>T

5 papers

NM_017449.5

p.D283H

c.847G>C

1 paper

NM_017449.5

p.S274F

c.821C>T

2 papers

NM_017449.5

p.S274A

c.820T>G

1 paper

NM_017449.5

p.P273L

c.818C>T

2 papers

NM_017449.5

p.P273insFs

c.817dupC

1 paper

NM_017449.5

p.C286S

c.856T>A

1 paper

NM_017449.5

p.C286Y

c.857G>A