Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.C286S

c.857G>C

Surrounding Variants

1 paper

NM_017449.5

p.C286Y

c.857G>A

1 paper

NM_017449.5

p.C286S

c.856T>A

1 paper

NM_017449.5

p.T287I

c.860C>T

1 paper

NM_017449.5

p.C289G

c.865T>G

5 papers

NM_017449.5

p.D283H

c.847G>C

1 paper

NM_017449.5

p.C289W

c.867T>G

2 papers

NM_017449.5

p.P290S

c.868C>T

3 papers

NM_017449.5

p.P290H

c.869C>A

1 paper

NM_017449.5

p.P290L

c.869C>T

1 paper

NM_017449.5

p.G282W

c.844G>T

1 paper

NM_017449.5

p.N292S

c.875A>G

1 paper

NM_017449.5

p.A279V

c.836C>T