Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.G299fs

c.895_896fs

Surrounding Variants

1 paper

NM_017449.5

p.G299R

c.895G>A

1 paper

NM_017449.5

p.G299E

c.896G>A

1 paper

NM_017449.5

p.A300insFs

c.899dupC

1 paper

NM_017449.5

p.A300_V304delFs

c.899_911del13

1 paper

NM_017449.5

p.A300V

c.899C>T

1 paper

NM_017449.5

p.N302_N307del6

c.904_920del18

1 paper

NM_017449.5

p.T295T

c.885C>T

1 paper

NM_017449.5

p.T295A

c.883A>G

1 paper

NM_017449.5

p.R294Q

c.881G>A

2 papers

NM_017449.5

p.R294W

c.880C>T

1 paper

NM_017449.5

p.N292S

c.875A>G

1 paper

NM_017449.5

p.C305C

c.915C>T