Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.R306_Y309del0

c.917_925del9

Surrounding Variants

2 papers

NM_017449.5

p.R306S

c.916C>A

3 papers

NM_017449.5

p.R306C

c.916C>T

1 paper

NM_017449.5

p.C305C

c.915C>T

1 paper

NM_017449.5

p.R306H

c.917G>A

1 paper

NM_017449.5

p.N307S

c.920A>G

1 paper

NM_017449.5

p.G308S

c.922G>A

2 papers

NM_017449.5

p.G308R

c.922G>C

1 paper

NM_017449.5

p.Y310S

c.929A>C

1 paper

NM_017449.5

p.N302_N307del6

c.904_920del18

1 paper

NM_017449.5

p.Y310Y

c.930C>T

1 paper

NM_017449.5

p.A312_D315del0

c.935_943del9

1 paper

NM_017449.5

p.A300V

c.899C>T