Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.A327P

c.979G>C

Surrounding Variants

2 papers

NM_017449.5

p.A327V

c.980C>T

1 paper

NM_017449.5

p.S326P

c.976T>C

1 paper

NM_017449.5

p.S326A

c.976T>G

2 papers

NM_017449.5

p.S326insFs

c.977_978insC

1 paper

NM_017449.5

p.P328H

c.983C>A

1 paper

NM_017449.5

p.P328L

c.983C>T

1 paper

NM_017449.5

p.A330delFs

c.988delG

1 paper

NM_017449.5

p.T323_I324insFs

c.969_970insG

4 papers

NM_017449.5

p.V331M

c.991G>A

1 paper

NM_017449.5

p.S333F

c.998C>T

1 paper

NM_017449.5

p.N336del1

c.1006_1007delAAT

1 paper

NM_017449.5

p.E337K

c.1009G>A