Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.N336del1

c.1006_1007delAAT

Surrounding Variants

1 paper

NM_017449.5

p.E337K

c.1009G>A

2 papers

NM_017449.5

p.T338insFs

c.1012_1013insT

1 paper

NM_017449.5

p.S333F

c.998C>T

1 paper

NM_017449.5

p.T338I

c.1013C>T

1 paper

NM_017449.5

p.S339A

c.1015T>G

2 papers

NM_017449.5

p.S339fs

c.1015_1016fs

1 paper

NM_017449.5

p.S339_L340delFs

c.1017_1018delCC

1 paper

NM_017449.5

p.S339F

c.1016C>T

4 papers

NM_017449.5

p.V331M

c.991G>A

2 papers

NM_017449.5

p.M341insFs

c.1022_1023insT

1 paper

NM_017449.5

p.M341T

c.1022T>C

1 paper

NM_017449.5

p.A330delFs

c.988delG