Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.S367_R369del3

c.1099_1106del9

Surrounding Variants

1 paper

NM_017449.5

p.G366S

c.1096G>A

1 paper

NM_017449.5

p.G366R

c.1096G>C

1 paper

NM_017449.5

p.C365Y

c.1094G>A

1 paper

NM_017449.5

p.G368D

c.1103G>A

1 paper

NM_017449.5

p.S364_C365insFs

c.1092_1093insG

2 papers

NM_017449.5

p.R369W

c.1105C>T

3 papers

NM_017449.5

p.R369Q

c.1106G>A

2 papers

NM_017449.5

p.A371V

c.1112C>T

1 paper

NM_017449.5

p.C372del1

c.1114_1116delTGC

5 papers

NM_017449.5

p.I361V

c.1081A>G

1 paper

NM_017449.5

p.I360T

c.1079T>C

1 paper

NM_017449.5

p.N359N

c.1077C>T