Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.Y404C

c.1211A>G

Surrounding Variants

1 paper

NM_017449.5

p.Q403*

c.1207C>T

1 paper

NM_017449.5

p.T405T

c.1215C>T

1 paper

NM_017449.5

p.T402T

c.1206C>G

1 paper

NM_017449.5

p.T402S

c.1205C>G

1 paper

NM_017449.5

p.F406S

c.1217T>C

1 paper

NM_017449.5

p.E407Q

c.1219G>C

1 paper

NM_017449.5

p.A400fs

c.1198_1199fs

1 paper

NM_017449.5

p.H401_T402del0

c.1201_1206del6

1 paper

NM_017449.5

p.L399P

c.1196T>C

1 paper

NM_017449.5

p.A410T

c.1228G>A

2 papers

NM_017449.5

p.D397_L398insFs

c.1191_1192insG

1 paper

NM_017449.5

p.N412Y

c.1234A>T