Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.T415N

c.1244C>A

Surrounding Variants

2 papers

NM_017449.5

p.V414L

c.1240G>C

1 paper

NM_017449.5

p.Q417*

c.1249C>T

1 paper

NM_017449.5

p.G413S

c.1237G>A

1 paper

NM_017449.5

p.N412N

c.1236C>T

1 paper

NM_017449.5

p.N412S

c.1235A>G

1 paper

NM_017449.5

p.N412Y

c.1234A>T

1 paper

NM_017449.5

p.P419S

c.1255C>T

1 paper

NM_017449.5

p.P419L

c.1256C>T

1 paper

NM_017449.5

p.P419P

c.1257C>T

1 paper

NM_017449.5

p.A410T

c.1228G>A

1 paper

NM_017449.5

p.S421A

c.1261T>G

1 paper

NM_017449.5

p.S421*

c.1262C>A