Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_017449.5

p.Q423Q

c.1269G>A

Surrounding Variants

1 paper

NM_017449.5

p.Q423P

c.1268A>C

1 paper

NM_017449.5

p.F424_V427del4

c.1270_1280del12

1 paper

NM_017449.5

p.F424L

c.1270T>C

1 paper

NM_017449.5

p.Q423*

c.1267C>T

1 paper

NM_017449.5

p.F424L

c.1272C>A

1 paper

NM_017449.5

p.F424L

c.1272C>G

1 paper

NM_017449.5

p.P422fs

c.1264_1265fs

1 paper

NM_017449.5

p.S421*

c.1262C>A

1 paper

NM_017449.5

p.S421L

c.1262C>T

2 papers

NM_017449.5

p.S426C

c.1277C>G

1 paper

NM_017449.5

p.S421A

c.1261T>G

1 paper

NM_017449.5

p.V427M

c.1279G>A