Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.G464R

c.1390G>C

Surrounding Variants

3 papers

NM_017449.5

p.G464A

c.1391G>C

7 papers

NM_017449.5

p.G464V

c.1391G>T

1 paper

NM_017449.5

p.N463S

c.1388A>G

1 paper

NM_017449.5

p.N463D

c.1387A>G

1 paper

NM_017449.5

p.V465M

c.1393G>A

2 papers

NM_017449.5

p.V465L

c.1393G>C

2 papers

NM_017449.5

p.V465L

c.1393G>T

1 paper

NM_017449.5

p.L467R

c.1400T>G

3 papers

NM_017449.5

p.P459P

c.1377G>A

1 paper

NM_017449.5

p.P459Q

c.1376C>A

1 paper

NM_017449.5

p.P459L

c.1376C>T

1 paper

NM_017449.5

p.Y469H

c.1405T>C