Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_017449.5

p.Y602C

c.1805A>G

Surrounding Variants

1 paper

NM_017449.5

p.Y602F

c.1805A>T

3 papers

NM_017449.5

p.T601A

c.1801A>G

15 papers

NM_017449.5

p.F600Y

c.1799T>A

1 paper

NM_017449.5

p.F600C

c.1799T>G

1 paper

NM_017449.5

p.F600_P605delins

c.1799_1815delinsAAAAG

1 paper

NM_017449.5

p.F600delins

c.1798delinsTACA

1 paper

NM_017449.5

p.P599_F600ins1

c.1797_1798insACA

1 paper

NM_017449.5

p.P599L

c.1796C>T

1 paper

NM_017449.5

p.F600ins1

c.1798_1799insCTT

1 paper

NM_017449.5

p.P605P

c.1815C>T

1 paper

NM_017449.5

p.P599_N606del0

c.1795_1818del24

1 paper

NM_017449.5

p.D598_P599ins1

c.1794_1795insGTT