Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_017449.5

p.R610W

c.1828C>T

Surrounding Variants

1 paper

NM_017449.5

p.R610L

c.1829G>T

1 paper

NM_017449.5

p.E611Q

c.1831G>C

1 paper

NM_017449.5

p.V609insFs

c.1826_1827insT

1 paper

NM_017449.5

p.A608V

c.1823C>T

1 paper

NM_017449.5

p.P605P

c.1815C>T

1 paper

NM_017449.5

p.E615K

c.1843G>A

1 paper

NM_017449.5

p.I616T

c.1847T>C

1 paper

NM_017449.5

p.I616I

c.1848T>A

1 paper

NM_017449.5

p.D617N

c.1849G>A

1 paper

NM_017449.5

p.D617Y

c.1849G>T

2 papers

NM_017449.5

p.D617G

c.1850A>G

2 papers

NM_017449.5

p.Y602C

c.1805A>G