Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.I618N

c.1853T>A

Surrounding Variants

1 paper

NM_017449.5

p.S619T

c.1855T>A

2 papers

NM_017449.5

p.D617G

c.1850A>G

1 paper

NM_017449.5

p.S619F

c.1856C>T

1 paper

NM_017449.5

p.D617N

c.1849G>A

1 paper

NM_017449.5

p.D617Y

c.1849G>T

2 papers

NM_017449.5

p.C620S

c.1858T>A

1 paper

NM_017449.5

p.I616I

c.1848T>A

3 papers

NM_017449.5

p.C620R

c.1858T>C

1 paper

NM_017449.5

p.C620G

c.1858T>G

2 papers

NM_017449.5

p.C620S

c.1859G>C

1 paper

NM_017449.5

p.C620insFs

c.1859_1860insC

3 papers

NM_017449.5

p.C620F

c.1859G>T