Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.C636S

c.1907G>C

Surrounding Variants

1 paper

NM_017449.5

p.C636F

c.1907G>T

1 paper

NM_017449.5

p.C636S

c.1906T>A

1 paper

NM_017449.5

p.C636insFs

c.1906_1907insC

1 paper

NM_017449.5

p.S637I

c.1910G>T

1 paper

NM_017449.5

p.E634E

c.1902G>A

1 paper

NM_017449.5

p.E634K

c.1900G>A

1 paper

NM_017449.5

p.F632L

c.1896T>A

1 paper

NM_017449.5

p.L642V

c.1924C>G

1 paper

NM_017449.5

p.L642P

c.1925T>C

1 paper

NM_017449.5

p.L642R

c.1925T>G

1 paper

NM_017449.5

p.P643T

c.1927C>A

1 paper

NM_017449.5

p.P643S

c.1927C>T