Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.T690I

c.2069C>T

Surrounding Variants

1 paper

NM_017449.5

p.T690T

c.2070C>A

1 paper

NM_017449.5

p.V689M

c.2065G>A

1 paper

NM_017449.5

p.S692N

c.2075G>A

1 paper

NM_017449.5

p.E700V

c.2099A>T

1 paper

NM_017449.5

p.E700D

c.2100G>C

1 paper

NM_017449.5

p.E700D

c.2100G>T

1 paper

NM_017449.5

p.H679_P680insFs

c.2037_2038insT

1 paper

NM_017449.5

p.H679N

c.2035C>A

1 paper

NM_017449.5

p.D678D

c.2034C>T

10 papers

NM_017449.5

p.D678N

c.2032G>A

NM_004442.7

p.D679N

c.2035G>A

1 paper

NM_017449.5

p.F677F

c.2031C>T

1 paper

NM_017449.5

p.E703K

c.2107G>A