Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.D739N

c.2215G>A

Surrounding Variants

1 paper

NM_017449.5

p.Y736F

c.2207A>T

1 paper

NM_017449.5

p.Y742F

c.2225A>T

1 paper

NM_004442.7

p.H745Y

c.2233C>T

7 papers

NM_017449.5

p.R745C

c.2233C>T

1 paper

NM_017449.5

p.R745H

c.2234G>A

1 paper

NM_017449.5

p.A731V

c.2192C>T

1 paper

NM_017449.5

p.A731T

c.2191G>A

1 paper

NM_017449.5

p.G729A

c.2186G>C

1 paper

NM_017449.5

p.A749P

c.2245G>C

1 paper

NM_017449.5

p.R728Q

c.2183G>A

2 papers

NM_017449.5

p.R728W

c.2182C>T

1 paper

NM_017449.5

p.R750C

c.2248C>T