Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.S776A

c.2326T>G

Surrounding Variants

1 paper

NM_017449.5

p.T779_Y780delFs

c.2335_2338del4

1 paper

NM_017449.5

p.T779S

c.2335A>T

1 paper

NM_017449.5

p.D773delFs

c.2318_2319delAC

1 paper

NM_017449.5

p.T779S

c.2336C>G

1 paper

NM_017449.5

p.S782N

c.2345G>A

1 paper

NM_017449.5

p.R769H

c.2306G>A

1 paper

NM_017449.5

p.S782R

c.2346T>A

1 paper

NM_017449.5

p.A783V

c.2348C>T

1 paper

NM_017449.5

p.L784insFs

c.2352dupG

1 paper

NM_017449.5

p.F765delFs

c.2294_2295delTT

1 paper

NM_017449.5

p.C760S

c.2279G>C

1 paper

NM_017449.5

p.C760S

c.2278T>A