Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_017449.5

p.R844Q

c.2531G>A

Surrounding Variants

1 paper

NM_017449.5

p.R844G

c.2530C>G

1 paper

NM_017449.5

p.R844W

c.2530C>T

1 paper

NM_017449.5

p.L845P

c.2534T>C

8 papers

NM_017449.5

p.D842V

c.2525A>T

1 paper

NM_017449.5

p.D842Y

c.2524G>T

1 paper

NM_017449.5

p.I839M

c.2517T>G

1 paper

NM_017449.5

p.I839T

c.2516T>C

1 paper

NM_017449.5

p.A838A

c.2514C>T

1 paper

NM_017449.5

p.A838T

c.2512G>A

1 paper

NM_017449.5

p.C851S

c.2551T>A

1 paper

NM_017449.5

p.N837S

c.2510A>G

1 paper

NM_017449.5

p.C851Y

c.2552G>A