Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_017449.5

p.D861N

c.2581G>A

Surrounding Variants

1 paper

NM_017449.5

p.D861Y

c.2581G>T

1 paper

NM_017449.5

p.D861G

c.2582A>G

1 paper

NM_017449.5

p.L860M

c.2578C>A

1 paper

NM_017449.5

p.L860L

c.2578C>T

1 paper

NM_017449.5

p.C862S

c.2584T>A

1 paper

NM_017449.5

p.C862S

c.2585G>C

2 papers

NM_017449.5

p.L858H

c.2573T>A

60 papers

NM_017449.5

p.L858R

c.2573T>G

2 papers

NM_017449.5

p.L858F

c.2572C>T

1 paper

NM_017449.5

p.Q864*

c.2590C>T

5 papers

NM_017449.5

p.Q857*

c.2569C>T

1 paper

NM_017449.5

p.L855Q

c.2564T>A