Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.R870Q

c.2609G>A

Surrounding Variants

1 paper

NM_017449.5

p.P871L

c.2612C>T

1 paper

NM_017449.5

p.F873I

c.2617T>A

2 papers

NM_017449.5

p.R867H

c.2600G>A

1 paper

NM_017449.5

p.G874S

c.2620G>A

1 paper

NM_017449.5

p.G874D

c.2621G>A

1 paper

NM_017449.5

p.Q875E

c.2623C>G

1 paper

NM_017449.5

p.Q864*

c.2590C>T

1 paper

NM_017449.5

p.C862S

c.2585G>C

1 paper

NM_017449.5

p.N878K

c.2634C>A

1 paper

NM_017449.5

p.N878K

c.2634C>G

1 paper

NM_017449.5

p.C862S

c.2584T>A

1 paper

NM_017449.5

p.D861G

c.2582A>G