Varaico: Literature-Extracted Genetic Variants

EPHB2

2,780 papers

RefSeq Summary

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a trans...

Pfam Domains

Ephrin_lbdaa 21–197UCSCEphrin receptor ligand binding domain

Ephrin_CRDaa 198–256UCSCEphrin cysteine rich domain

Ephrin_rec_likeaa 260–304UCSCTyrosine-protein kinase ephrin type A/B receptor-like

fn3aa 326–427UCSCFibronectin type III domain

fn3aa 434–526UCSCFibronectin type III domain

EphA2_TMaa 544–618UCSCEphrin type-A receptor 2 transmembrane domain

Gene Aliases

HGNC Name

EPH receptor B2

HGNC Previous Symbols

DRT; ERK; EPHT3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017449.5

p.A892P

c.2674G>C

Surrounding Variants

1 paper

NM_017449.5

p.A892fs

c.2674_2675fs

1 paper

NM_017449.5

p.L890F

c.2668C>T

1 paper

NM_017449.5

p.S889G

c.2665A>G

1 paper

NM_017449.5

p.N888I

c.2663A>T

1 paper

NM_017449.5

p.S897A

c.2689T>G

1 paper

NM_017449.5

p.S897delFs

c.2690delC

1 paper

NM_017449.5

p.N886I

c.2657A>T

1 paper

NM_017449.5

p.N886H

c.2656A>C

1 paper

NM_017449.5

p.S898fs

c.2692_2693fs

1 paper

NM_017449.5

p.R885H

c.2654G>A

1 paper

NM_017449.5

p.R885C

c.2653C>T

2 papers

NM_017449.5

p.G899S

c.2695G>A