Varaico: Literature-Extracted Genetic Variants

Gene:ERCC5
Variant:p.A874S

ERCC5

1,002 papers

RefSeq Summary

This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, in...

Pfam Domains

XPG_Naa 1–98UCSCXPG N-terminal domain
XPG_Iaa 780–861UCSCXPG I-region

Gene Aliases

HGNC Name

ERCC excision repair 5, endonuclease

HGNC Previous Symbols

ERCM2; XPGC

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000123.4
p.A874S
c.2620G>T
Surrounding Variants
20 papers
NM_000123.4
p.A874T
c.2620G>A
1 paper
NM_000123.4
p.T873N
c.2618C>A
1 paper
NM_000123.4
p.M875I
c.2625G>A
1 paper
NM_000123.4
p.M875I
c.2625G>C
1 paper
NM_000123.4
p.M875I
c.2625G>T
1 paper
NM_000123.4
p.C871F
c.2612G>T
1 paper
NM_000123.4
p.I877N
c.2630T>A
2 papers
NM_000123.4
p.L878V
c.2632C>G
1 paper
NM_000123.4
p.G870S
c.2608G>A
1 paper
NM_000123.4
p.V869fs
c.2605_2606fs
3 papers
NM_000123.4
p.V869fs
c.2605_2606fs
10 papers
NM_000123.4
p.N879S
c.2636A>G
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