Varaico: Literature-Extracted Genetic Variants

Gene:EXO1
Variant:p.G274E

EXO1

925 papers

RefSeq Summary

This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involve...

Pfam Domains

XPG_Naa 1–99UCSCXPG N-terminal domain
XPG_Iaa 141–225UCSCXPG I-region

Gene Aliases

HGNC Name

exonuclease 1

HGNC Alias Symbols

HEX1; hExoI

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_130398.4
p.G274E
c.821G>A
Surrounding Variants
13 papers
NM_130398.4
p.G274R
c.820G>A
11 papers
NM_130398.4
p.G274R
c.820G>C
1 paper
NM_130398.4
p.N273I
c.818A>T
1 paper
NM_130398.4
p.F275Y
c.824T>A
1 paper
NM_130398.4
p.I272I
c.816C>T
1 paper
NM_130398.4
p.Y271H
c.811T>C
1 paper
NM_130398.4
p.D270D
c.810T>C
2 papers
NM_130398.4
p.D270V
c.809A>T
18 papers
NM_130398.4
p.N279S
c.836A>G
2 papers
NM_130398.4
p.N280S
c.839A>G
1 paper
NM_130398.4
p.P268L
c.803C>T
1 paper
NM_130398.4
p.P268S
c.802C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."