Varaico: Literature-Extracted Genetic Variants

Gene:EXO1
Variant:p.L453W

EXO1

925 papers

RefSeq Summary

This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involve...

Pfam Domains

XPG_Naa 1–99UCSCXPG N-terminal domain
XPG_Iaa 141–225UCSCXPG I-region

Gene Aliases

HGNC Name

exonuclease 1

HGNC Alias Symbols

HEX1; hExoI

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_130398.4
p.L453W
c.1358T>G
Surrounding Variants
1 paper
NM_130398.4
p.L453F
c.1359G>C
1 paper
NM_130398.4
p.L453F
c.1359G>T
1 paper
NM_130398.4
p.S456A
c.1366T>G
1 paper
NM_130398.4
p.N450S
c.1349A>G
1 paper
NM_130398.4
p.S456Y
c.1367C>A
1 paper
NM_130398.4
p.S456C
c.1367C>G
9 papers
NM_130398.4
p.V458M
c.1372G>A
1 paper
NM_130398.4
p.S447_E448ins0
c.1339_1344dup6
4 papers
NM_130398.4
p.V460L
c.1378G>C
4 papers
NM_130398.4
p.V460L
c.1378G>T
1 paper
NM_130398.4
p.S446N
c.1337G>A
1 paper
NM_130398.4
p.S446G
c.1336A>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."