Varaico: Literature-Extracted Genetic Variants

Gene:EXO1
Variant:p.E589K

EXO1

925 papers

RefSeq Summary

This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involve...

Pfam Domains

XPG_Naa 1–99UCSCXPG N-terminal domain
XPG_Iaa 141–225UCSCXPG I-region

Gene Aliases

HGNC Name

exonuclease 1

HGNC Alias Symbols

HEX1; hExoI

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
31 papers
NM_130398.4
p.E589K
c.1765G>A
Surrounding Variants
1 paper
NM_130398.4
p.S590N
c.1769G>A
1 paper
NM_130398.4
p.S587A
c.1759T>G
2 papers
NM_130398.4
p.Y586C
c.1757A>G
1 paper
NM_130398.4
p.K592delFs
c.1774_1775delAA
1 paper
NM_130398.4
p.K592T
c.1775A>C
1 paper
NM_130398.4
p.S585P
c.1753T>C
1 paper
NM_130398.4
p.E584Q
c.1750G>C
1 paper
NM_130398.4
p.E583D
c.1749A>C
1 paper
NM_130398.4
p.E583D
c.1749A>T
1 paper
NM_130398.4
p.T594I
c.1781C>T
1 paper
NM_130398.4
p.E583G
c.1748A>G
1 paper
NM_130398.4
p.R595S
c.1785G>T
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