Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000504.4

p.L7I

c.19C>A

Surrounding Variants

1 paper

NM_000504.4

p.H6Y

c.16C>T

3 papers

NM_000504.4

p.V8F

c.22G>T

1 paper

NM_000504.4

p.L5Q

c.14T>A

1 paper

NM_000504.4

p.L9Q

c.26T>A

1 paper

NM_000504.4

p.L9P

c.26T>C

1 paper

NM_000504.4

p.L10I

c.28C>A

1 paper

NM_000504.4

p.P4S

c.10C>T

1 paper

NM_000504.4

p.L10F

c.28C>T

1 paper

NM_000504.4

p.R3R

c.9C>G

2 papers

NM_000504.4

p.L10L

c.30C>T

1 paper

NM_000504.4

p.S11R

c.31A>C

1 paper

NM_000504.4

p.R3S

c.7C>A