Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_000504.4

p.A15T

c.43G>A

Surrounding Variants

5 papers

NM_000504.4

p.A15D

c.44C>A

1 paper

NM_000504.4

p.L14P

c.41T>C

1 paper

NM_000504.4

p.L14R

c.41T>G

2 papers

NM_000504.4

p.L14L

c.40C>T

2 papers

NM_000504.4

p.G16S

c.46G>A

1 paper

NM_000504.4

p.A12P

c.34G>C

1 paper

NM_000504.4

p.S11R

c.33T>A

1 paper

NM_000504.4

p.S11R

c.33T>G

1 paper

NM_000504.4

p.S11R

c.31A>C

2 papers

NM_000504.4

p.L19L

c.55C>T

2 papers

NM_000504.4

p.L10L

c.30C>T

1 paper

NM_000504.4

p.L19P

c.56T>C