Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000504.4

p.L24Splc

c.70+2T>G

Surrounding Variants

4 papers

NM_000504.4

p.L24Splc

c.70+3A>T

5 papers

NM_000504.4

p.L24Splc

c.70+1G>A

2 papers

NM_000504.4

p.L24Splc

c.70+4A>G

1 paper

NM_000504.4

p.L24M

c.70C>A

1 paper

NM_000504.4

p.L24Splc

c.70+5G>A

1 paper

NM_000504.4

p.L24Splc

c.70+5G>C

1 paper

NM_000504.4

p.L24Splc

c.70+5G>T

1 paper

NM_000504.4

p.S23insFs

c.68dupG

1 paper

NM_000504.4

p.E22V

c.65A>T

1 paper

NM_000504.4

p.E22Q

c.64G>C

1 paper

NM_000504.4

p.G21E

c.62G>A

8 papers

NM_000504.4

p.G21R

c.61G>A