Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000504.4

p.C129S

c.386G>C

Surrounding Variants

1 paper

NM_000504.4

p.S130R

c.390C>G

1 paper

NM_000504.4

p.K127K

c.381G>A

2 papers

NM_000504.4

p.L128delFs

c.382delC

1 paper

NM_000504.4

p.L131P

c.392T>C

1 paper

NM_000504.4

p.R126R

c.378G>T

1 paper

NM_000504.4

p.R126W

c.376C>T

9 papers

NM_000504.4

p.G134R

c.400G>A

7 papers

NM_000504.4

p.G134R

c.400G>C

1 paper

NM_000504.4

p.F124delFs

c.372delC

1 paper

NM_000504.4

p.F124delFs

c.371delT

1 paper

NM_000504.4

p.D135V

c.404A>T

1 paper

NM_000504.4

p.D135E

c.405C>A