Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000504.4

p.F139L

c.415T>C

Surrounding Variants

2 papers

NM_000504.4

p.Q138L

c.413A>T

1 paper

NM_000504.4

p.F139L

c.417C>A

1 paper

NM_000504.4

p.F139L

c.417C>G

1 paper

NM_000504.4

p.C140R

c.418T>C

1 paper

NM_000504.4

p.C140Y

c.419G>A

1 paper

NM_000504.4

p.C140W

c.420C>G

1 paper

NM_000504.4

p.H141D

c.421C>G

1 paper

NM_000504.4

p.H141Q

c.423C>G

14 papers

NM_000504.4

p.E142K

c.424G>A

1 paper

NM_000504.4

p.C136R

c.406T>C

1 paper

NM_000504.4

p.D135E

c.405C>A

1 paper

NM_000504.4

p.D135E

c.405C>G