Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000504.4

p.G173R

c.517G>A

Surrounding Variants

1 paper

NM_000504.4

p.G173R

c.517G>C

1 paper

NM_000504.4

p.G173W

c.517G>T

3 papers

NM_000504.4

p.C172W

c.516T>G

1 paper

NM_000504.4

p.C172Y

c.515G>A

1 paper

NM_000504.4

p.G173_K174insFs

c.519_520insC

1 paper

NM_000504.4

p.C172F

c.515G>T

1 paper

NM_000504.4

p.C172R

c.514T>C

1 paper

NM_000504.4

p.C172G

c.514T>G

4 papers

NM_000504.4

p.C172delFs

c.514delT

2 papers

NM_000504.4

p.T176_Q186del0

c.526_558del33

1 paper

NM_000504.4

p.Q175_S183ins3

c.524_547dup24

2 papers

NM_000504.4

p.Q175*

c.523C>T