Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000504.4

p.R179C

c.535C>T

Surrounding Variants

1 paper

NM_000504.4

p.R180_K181insFs

c.540_543dup4

1 paper

NM_000504.4

p.E178K

c.532G>A

1 paper

NM_000504.4

p.L177_R182del0

c.529_546del18

1 paper

NM_000504.4

p.T176A

c.526A>G

1 paper

NM_000504.4

p.R182G

c.544A>G

1 paper

NM_000504.4

p.R182M

c.545G>T

1 paper

NM_000504.4

p.Q175R

c.524A>G

1 paper

NM_000504.4

p.Q175_S183ins3

c.524_547dup24

2 papers

NM_000504.4

p.Q175*

c.523C>T

2 papers

NM_000504.4

p.T176_Q186del0

c.526_558del33

1 paper

NM_000504.4

p.G173_K174insFs

c.519_520insC

1 paper

NM_000504.4

p.V184A

c.551T>C