Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000504.4

p.S191delFs

c.573delC

Surrounding Variants

1 paper

NM_000504.4

p.S191_G192insA

c.571_575ins3

4 papers

NM_000504.4

p.G192R

c.574G>A

4 papers

NM_000504.4

p.G192R

c.574G>C

1 paper

NM_000504.4

p.S189N

c.566G>A

1 paper

NM_000504.4

p.A194V

c.581C>T

1 paper

NM_000504.4

p.Q186R

c.557A>G

1 paper

NM_000504.4

p.I198_T199del1

c.593_595delTCA

1 paper

NM_000504.4

p.Q186delFs

c.556delC

1 paper

NM_000504.4

p.V184A

c.551T>C

1 paper

NM_000504.4

p.T199_Y203delFs

c.595_607del13

1 paper

NM_000504.4

p.W200*

c.599G>A

1 paper

NM_000504.4

p.R182M

c.545G>T