Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000504.4

p.G238C

c.712G>T

Surrounding Variants

1 paper

NM_000504.4

p.G238A

c.713G>C

1 paper

NM_000504.4

p.G237E

c.710G>A

1 paper

NM_000504.4

p.G237*

c.709G>T

6 papers

NM_000504.4

p.V236M

c.706G>A

1 paper

NM_000504.4

p.C241delFs

c.723delC

1 paper

NM_000504.4

p.K242delins

c.726delinsCCAT

1 paper

NM_000504.4

p.D243N

c.727G>A

1 paper

NM_000504.4

p.L232P

c.695T>C

10 papers

NM_000504.4

p.G244R

c.730G>A

10 papers

NM_000504.4

p.G244R

c.730G>C

1 paper

NM_000504.4

p.C246S

c.736T>A

1 paper

NM_000504.4

p.C246R

c.736T>C