Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000504.4

p.H276Q

c.828C>A

Surrounding Variants

1 paper

NM_000504.4

p.H276Q

c.828C>G

1 paper

NM_000504.4

p.C277Y

c.830G>A

3 papers

NM_000504.4

p.A275V

c.824C>T

2 papers

NM_000504.4

p.A275T

c.823G>A

1 paper

NM_000504.4

p.Y279S

c.836A>C

1 paper

NM_000504.4

p.Y279C

c.836A>G

1 paper

NM_000504.4

p.A274S

c.820G>T

2 papers

NM_000504.4

p.Y279*

c.837C>A

2 papers

NM_000504.4

p.Y279*

c.837C>G

1 paper

NM_000504.4

p.Q280K

c.838C>A

2 papers

NM_000504.4

p.T273M

c.818C>T

1 paper

NM_000504.4

p.Q280H

c.840A>C