Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000504.4

p.K285M

c.854A>T

Surrounding Variants

1 paper

NM_000504.4

p.K285E

c.853A>G

2 papers

NM_000504.4

p.V286M

c.856G>A

1 paper

NM_000504.4

p.R287W

c.859A>T

2 papers

NM_000504.4

p.V288A

c.863T>C

1 paper

NM_000504.4

p.V288_G289insFs

c.864_865insT

2 papers

NM_000504.4

p.G289R

c.865G>A

3 papers

NM_000504.4

p.G289R

c.865G>C

1 paper

NM_000504.4

p.Q280H

c.840A>C

1 paper

NM_000504.4

p.Q280H

c.840A>T

1 paper

NM_000504.4

p.Q280K

c.838C>A

1 paper

NM_000504.4

p.G289Splc

c.865+5G>A

2 papers

NM_000504.4

p.Y279*

c.837C>A