Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_000504.4

p.G289Splc

c.866-1G>A

Surrounding Variants

1 paper

NM_000504.4

p.G289Splc

c.866-4C>A

6 papers

NM_000504.4

p.R291W

c.871C>T

1 paper

NM_000504.4

p.R291Q

c.872G>A

1 paper

NM_000504.4

p.N292insFs

c.875_876insT

2 papers

NM_000504.4

p.N292_T293insFs

c.876_877insT

1 paper

NM_000504.4

p.T293M

c.878C>T

1 paper

NM_000504.4

p.Q295insFs

c.883dupC

1 paper

NM_000504.4

p.E297K

c.889G>A

1 paper

NM_000504.4

p.A301_V307del0

c.902_919del18

1 paper

NM_000504.4

p.A301T

c.901G>A

2 papers

NM_000504.4

p.E304K

c.910G>A

1 paper

NM_000504.4

p.V305V

c.915G>A