Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000504.4

p.E304K

c.910G>A

Surrounding Variants

1 paper

NM_000504.4

p.V305V

c.915G>A

1 paper

NM_000504.4

p.A301T

c.901G>A

2 papers

NM_000504.4

p.V308I

c.922G>A

1 paper

NM_000504.4

p.V308insFs

c.923dupT

1 paper

NM_000504.4

p.A301_V307del0

c.902_919del18

1 paper

NM_000504.4

p.H311_N312ins5

c.931_935ins15

1 paper

NM_000504.4

p.E297K

c.889G>A

1 paper

NM_000504.4

p.N312Fs

c.934_936delinsCFs

1 paper

NM_000504.4

p.N312delins

c.936delinsC

1 paper

NM_000504.4

p.Q295insFs

c.883dupC

1 paper

NM_000504.4

p.T315_T318del4

c.943_953del12

1 paper

NM_000504.4

p.T293M

c.878C>T