Varaico: Literature-Extracted Genetic Variants

F10

519 papers

RefSeq Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-c...

Pfam Domains

Glaaa 45–85UCSCVitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

EGFaa 90–120UCSCEGF-like domain

FXa_inhibitionaa 129–164UCSCCoagulation Factor Xa inhibitory site

Trypsinaa 235–311UCSCTrypsin

Gene Aliases

HGNC Name

coagulation factor X

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_000504.4

p.R327W

c.979C>T

Surrounding Variants

1 paper

NM_000504.4

p.I323M

c.969C>G

4 papers

NM_000504.4

p.D322N

c.964G>A

1 paper

NM_000504.4

p.F321L

c.963C>A

1 paper

NM_000504.4

p.F321L

c.963C>G

1 paper

NM_000504.4

p.F321L

c.961T>C

1 paper

NM_000504.4

p.D320delFs

c.960delC

1 paper

NM_000504.4

p.D320H

c.958G>C

2 papers

NM_000504.4

p.Y319C

c.956A>G

1 paper

NM_000504.4

p.Y319H

c.955T>C

1 paper

NM_000504.4

p.T318I

c.953C>T

1 paper

NM_000504.4

p.M336V

c.1006A>G

2 papers

NM_000504.4

p.E317E

c.951G>A